hm..not sure if im intrepreting yur question right. because it seems like a very broad question that could be intrepreted in many ways..

what about the word "HIV"? cuz there's a long history about it...in a simplistic nutshell.

culture: how it was first seen as a gay men's disease...cuz it occured in them first....
language: but politics got in the way and refused to admit to the science and they just relate it to poverty/gay ppl.

is that what u mean?